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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ESPL1 All Species: 15.76
Human Site: T285 Identified Species: 49.52
UniProt: Q14674 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14674 NP_036423.4 2120 233113 T285 A H S Y L R N T N L A P S L Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103494 2120 233105 T285 A H S Y L R N T N L A P S L Q
Dog Lupus familis XP_849828 2116 232497 T293 A H K Y L R D T D L A P S L Q
Cat Felis silvestris
Mouse Mus musculus P60330 2118 233016 T285 A R N H L E K T S V A P S L Q
Rat Rattus norvegicus NP_001164073 2109 231597 S285 T R D H L G N S N V A P S L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423289 1597 172559
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001337869 2182 240839 L282 E V N G H V G L R S A L G L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_782226 2231 246313 I312 V C A I C D V I R I S L S L S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.9 82.3 N.A. 77.3 77.8 N.A. N.A. 27.1 N.A. 34.6 N.A. N.A. N.A. N.A. 22.4
Protein Similarity: 100 N.A. 97.7 88.2 N.A. 85.4 85.7 N.A. N.A. 40 N.A. 52.3 N.A. N.A. N.A. N.A. 40.7
P-Site Identity: 100 N.A. 100 80 N.A. 53.3 53.3 N.A. N.A. 0 N.A. 13.3 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 N.A. 100 93.3 N.A. 80 73.3 N.A. N.A. 0 N.A. 20 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 13 0 0 0 0 0 0 0 75 0 0 0 13 % A
% Cys: 0 13 0 0 13 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 13 0 0 13 13 0 13 0 0 0 0 0 0 % D
% Glu: 13 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 13 0 13 13 0 0 0 0 0 13 0 0 % G
% His: 0 38 0 25 13 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 13 0 0 0 13 0 13 0 0 0 0 0 % I
% Lys: 0 0 13 0 0 0 13 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 63 0 0 13 0 38 0 25 0 88 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 25 0 0 0 38 0 38 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 63 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63 % Q
% Arg: 0 25 0 0 0 38 0 0 25 0 0 0 0 0 0 % R
% Ser: 0 0 25 0 0 0 0 13 13 13 13 0 75 0 13 % S
% Thr: 13 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % T
% Val: 13 13 0 0 0 13 13 0 0 25 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 38 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _